A weekly podcast for physicians interested in evidence based medicine and rheumatology. Find the papers at ebrheum.com
Episodes
Thursday Mar 06, 2025
Thursday Mar 06, 2025
What do you do when observational data and RCTs conflict? This week I'm covering the "real world PEXIVAS" study that was done by the French Vasculitis Study Group. Great read, interesting issues, have a listen and be sure to share with friends!
Monday Feb 10, 2025
Monday Feb 10, 2025
One of my rare case-report podcasts, a topic that I typically avoid. The craze about CAR-T has also made me a little crazy, though, so I wanted to share what I think may be the ultimate destination for "more B cell depletion than rituximab" strategies.
Article: https://www.nejm.org/doi/full/10.1056/NEJMc2407150
Friday Jan 31, 2025
Friday Jan 31, 2025
Podcast this week about overdiagnosis! Currently one of my favorite topics and something that I think will be an emerging issue in our field. We recently published a Viewpoint in Lancet Rheumatology (https://pubmed.ncbi.nlm.nih.gov/39341221/) addressing this issue. I'm going to read from it and after that will be giving a few final (spicy) thoughts on the topic. Hope you find it worthwhile! s
Tuesday Dec 03, 2024
Tuesday Dec 03, 2024
New RCT in a new disease with a new drug! But is it as shiny as one would hope? Interesting discussion today about what a trial means, how it will affect practice, and how we could do better as a field. Happy holidays everyone!
Monday Nov 11, 2024
Monday Nov 11, 2024
Reading one of my recent newsletters this week, this one about PMR tapers. Be sure to subscribe at ebrheum.com if you want access to the visuals and upcoming editions!
Monday Oct 28, 2024
Monday Oct 28, 2024
Quick rundown of an important rheumatology RCT this week, discussing the IL-5 inhibitor benralizumab for the treatment of relapsing/refractory EGPA.
MANDARA Study: https://www.nejm.org/doi/full/10.1056/NEJMoa2311155
Monday Oct 14, 2024
Monday Oct 14, 2024
Important methodology podcast this week, covering a lot of ground with expert epidemiologist Rishi Desai. Really enjoyed our conversation and glad to be publishing today!
**House Keeping Note: we actually recorded this ~15 months ago but I somehow lost the audio... which somehow re-appeared! #technology
STAR-RA: https://pubmed.ncbi.nlm.nih.gov/35027405/
Monday Sep 30, 2024
Monday Sep 30, 2024
Exciting podcast this week about the upcoming / impending use of CAR-T in rheumatology. Highly recommend rheumatologists learn about this now; it's going to be a big thing for many years to come. In a future episode I will lay out my case for skepticism, but for now I think a good run down of the first big published series will be enough!
NEJM CAR-T Case Series: https://www.nejm.org/doi/full/10.1056/NEJMoa2308917
Nature Review Article: https://www.nature.com/articles/s41584-024-01139-z
Thursday Sep 12, 2024
Thursday Sep 12, 2024
This week's podcast will be a quick read of one of my newsletters. The title basically speaks for itself! Find the newsletter and my other work at ebrheum.com
Monday Mar 25, 2024
Monday Mar 25, 2024
At ACR23 I had a twitter-disagreement about steroid tapers from PEXIVAS with Mike Walsh, the lead author on the PEXIVAS trial. He kindly agreed to join me for a moderated discussion. Loved hearing his perspective and have to admit he pulled me closer to his practice... but not all the way there. Longer podcast than usual but I prefer to release audio uncut and this took as long as it needed! Hoping y'all enjoy.
Articles referenced during the podcast:
PEXIVAS: https://www.nejm.org/doi/full/10.1056/nejmoa1803537
PEXIVAS DAH Subset: https://www.atsjournals.org/doi/10.1164/rccm.202308-1426OC
Walsh Meta Analysis: https://pubmed.ncbi.nlm.nih.gov/35217545/