Episodes
Monday Nov 11, 2024
E116: A New Paradigm for PMR
Monday Nov 11, 2024
Monday Nov 11, 2024
Reading one of my recent newsletters this week, this one about PMR tapers. Be sure to subscribe at ebrheum.com if you want access to the visuals and upcoming editions!
Monday Oct 28, 2024
E115: Benralizumab for EGPA - the MANDARA Study
Monday Oct 28, 2024
Monday Oct 28, 2024
Quick rundown of an important rheumatology RCT this week, discussing the IL-5 inhibitor benralizumab for the treatment of relapsing/refractory EGPA.
MANDARA Study: https://www.nejm.org/doi/full/10.1056/NEJMoa2311155
Monday Oct 14, 2024
E114: Target Trials and STAR-RA with Rishi Desai
Monday Oct 14, 2024
Monday Oct 14, 2024
Important methodology podcast this week, covering a lot of ground with expert epidemiologist Rishi Desai. Really enjoyed our conversation and glad to be publishing today!
**House Keeping Note: we actually recorded this ~15 months ago but I somehow lost the audio... which somehow re-appeared! #technology
STAR-RA: https://pubmed.ncbi.nlm.nih.gov/35027405/
Monday Sep 30, 2024
E113: CAR-T is Coming to Rheumatology
Monday Sep 30, 2024
Monday Sep 30, 2024
Exciting podcast this week about the upcoming / impending use of CAR-T in rheumatology. Highly recommend rheumatologists learn about this now; it's going to be a big thing for many years to come. In a future episode I will lay out my case for skepticism, but for now I think a good run down of the first big published series will be enough!
NEJM CAR-T Case Series: https://www.nejm.org/doi/full/10.1056/NEJMoa2308917
Nature Review Article: https://www.nature.com/articles/s41584-024-01139-z
Thursday Sep 12, 2024
E112: Gabapentin is Trash
Thursday Sep 12, 2024
Thursday Sep 12, 2024
This week's podcast will be a quick read of one of my newsletters. The title basically speaks for itself! Find the newsletter and my other work at ebrheum.com
Monday Mar 25, 2024
E111: PEXIVAS Subsets with Mike Walsh & Mats Junek
Monday Mar 25, 2024
Monday Mar 25, 2024
At ACR23 I had a twitter-disagreement about steroid tapers from PEXIVAS with Mike Walsh, the lead author on the PEXIVAS trial. He kindly agreed to join me for a moderated discussion. Loved hearing his perspective and have to admit he pulled me closer to his practice... but not all the way there. Longer podcast than usual but I prefer to release audio uncut and this took as long as it needed! Hoping y'all enjoy.
Articles referenced during the podcast:
PEXIVAS: https://www.nejm.org/doi/full/10.1056/nejmoa1803537
PEXIVAS DAH Subset: https://www.atsjournals.org/doi/10.1164/rccm.202308-1426OC
Walsh Meta Analysis: https://pubmed.ncbi.nlm.nih.gov/35217545/
Thursday Mar 14, 2024
E110: Rheum4Debate - Screening for RA-ILD with Joshua Solomon and Scott Matson
Thursday Mar 14, 2024
Thursday Mar 14, 2024
Rheum4Debate is back!
In this episode I moderated a debate between two pulmonologists about RA-ILD. As a reminder, Rheum4Debate is an Oxford-style debate show, where two debators disagree over a motion during 3 rounds of discussion. The motion for todays show was:
“Asymptomatic patients with rheumatoid arthritis and high risk features for interstitial lung disease should be screened using pulmonary function testing and a high resolution CT scan”
Joshua defended the motion and Scott argued against it. I thoroughly enjoyed the discussion and am sure you will as well!
Monday Mar 11, 2024
E109: Abatacept for Pre-RA - the ARIAA Study
Monday Mar 11, 2024
Monday Mar 11, 2024
Nice study this week on an important topic. Can we prevent the development of rheumatoid arthritis by initiating DMARDs during a preclinical phase? Lots to discuss: what does it mean to be "pre-clinical?" How does this fit with other studies of this nature?
Check it out! https://www.thelancet.com/journals/lancet/article/PIIS0140-6736(23)02650-8/fulltext
Monday Feb 26, 2024
E108: Myositis Guidelines for Cancer Screening w/Alexander Oldroyd
Monday Feb 26, 2024
Monday Feb 26, 2024
Informative podcast this week with Dr. Alexander Oldroyd, the first author of the recently published "International Guideline for Idiopathic Inflammatory Myopathy-Associated Cancer Screening." The article itself appeared in Nature Reviews Rheumatology and provides what I think is a very useful framework for approaching this issue.
Article: https://www.nature.com/articles/s41584-023-01045-w
Monday Feb 05, 2024
E107: Fragility of SLE Randomized Controlled Trials
Monday Feb 05, 2024
Monday Feb 05, 2024
Quick methodology episode this week discussing the concept of "fragility" in randomized controlled trials of lupus. Really enjoyed discussing this paper and was grateful to have been a part of it. Get the text here: https://lupus.bmj.com/content/lupusscimed/11/1/e001068.full.pdf